Mason clinched the win over Centerville 57-41 in a Division I girls district final on Saturday at Harrison High School.
Junior Briana Glover led three Comets scorers in double figures with 15 points and eight rebounds. She scored seven points in the last four minutes of the fourth quarter, preventing any hope of a Centerville comeback.
Jenna Gunn had 14 points while Sarah Hunter scored 10.
Mason advanced to a regional semifinal game against Kettering Fairmont at 6:15 p.m. Tuesday at Wright State.